![]() ![]() Lurie Children's is a nonprofit organization committed to providing access to exceptional care for every child. The Manne Research Institute is focused on improving child health, transforming pediatric medicine and ensuring healthier futures through the relentless pursuit of knowledge. ![]() Lurie Children's Hospital of Chicago is conducted through Stanley Manne Children's Research Institute. "We speculate that nailfold microvascular density quantification has the potential to help further characterize the link between the uterine environment, placental health and outcomes of preterm birth, so that we can improve those outcomes."Research at AnnRobert H. "The differences we found in microvascular density were most striking near birth, suggesting that perturbed microvascular development may begin in utero during the perinatal period, impacting organ microvascular development," said Dr. Microvascular density in the first month of life also correlated with the severity of ROP. De Plaen and colleagues found that nailbed capillary density was higher in babies who later developed ROP. In the cohort of 32 premature neonates they studied, Dr. It affects 33%-60% of babies with very low birth weight (less than 1,500g). Our findings might also lead to the development of earlier preventive or therapeutic interventions for ROP and other complications of prematurity associated with maldevelopment of microvasculature."ROP occurs in about 1/500-1/1,000 premature infants. "Earlier identification of these infants reduces the need to subject all premature babies to highly invasive eye exams. De Plaen, senior author and neonatologist at Lurie Children's, as well as Professor of Pediatrics at Northwestern University Feinberg School of Medicine. By measuring the nailbed capillary density soon after birth we can identify premature infants at higher risk for developing ROP long before it is detectable by an eye exam," said Dr. "Abnormal systemic vascular development starts much earlier than we thought. Findings were published in the Journal of Pediatrics. This screening could eliminate the need to evaluate all premature infants with eye exams about a month later. Isabelle De Plaen, MD, and colleagues found that imaging the capillaries in the nailbed of preemies within the first month of life using a non-invasive technique, called nailbed capillaroscopy, can identify infants at high risk for developing ROP. ROP is caused by an abnormal development of small blood vessels on the retina. Chicago, June 30 (ANI): Retinopathy of prematurity (ROP), the most common cause of preventable permanent blindness in children in the U.S., has been the subject of extensive research at AnnRobert H. ![]()
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